Tupichinol A

CAS# 497142-88-8

Tupichinol A

Catalog No. BCN7697----Order now to get a substantial discount!

Product Name & Size Price Stock
Tupichinol A: 5mg $1098 In Stock
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Quality Control of Tupichinol A

Number of papers citing our products

Chemical structure

Tupichinol A

3D structure

Chemical Properties of Tupichinol A

Cas No. 497142-88-8 SDF Download SDF
PubChem ID 637885 Appearance Powder
Formula C17H18O4 M.Wt 286.32
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3R)-2-(4-hydroxyphenyl)-7-methoxy-8-methyl-3,4-dihydro-2H-chromen-3-ol
SMILES CC1=C(C=CC2=C1OC(C(C2)O)C3=CC=C(C=C3)O)OC
Standard InChIKey PSCVPMJLJOIQKC-RHSMWYFYSA-N
Standard InChI InChI=1S/C17H18O4/c1-10-15(20-2)8-5-12-9-14(19)17(21-16(10)12)11-3-6-13(18)7-4-11/h3-8,14,17-19H,9H2,1-2H3/t14-,17-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Tupichinol A

The underground parts of Tupistra chinensis.

Biological Activity of Tupichinol A

DescriptionTupichinol A is a natural product from Tupistra chinensis.
In vitro

New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity.[Pubmed: 12608845]

J Nat Prod. 2003 Feb;66(2):161-8.


METHODS AND RESULTS:
Seven new compounds, including three new flavans [Tupichinol A,tupichinol B, tupichinol C (1-3)], three new spirostanol sapogenins [tupichigenin D, tupichigenin E, tupichigenin F (4-6)], and one new pregnane genin [tupipregnenolone (7)], together with 18 known compounds, were isolated from the underground parts of Tupistra chinensis. The structures of the new compounds were elucidated by spectroscopic analysis and chemical evidence. The structures and relative stereochemistry of 1 and 9 were further confirmed by single-crystal X-ray crystallographic analysis.
CONCLUSIONS:
Compounds Delta(25(27))-pentrogenin, 10, and ranmogenin A showed 100%, 96%, and 80% inhibition, respectively, against human gastric tumor (NUGC) cells at a concentration of 50 microM. Delta(25(27))-pentrogenin showed 100% inhibition against human nasopharyngeal carcinoma (HONE-1) cells at a concentration of 50 microM.

Tupichinol A Dilution Calculator

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Tupichinol A Molarity Calculator

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Preparing Stock Solutions of Tupichinol A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4926 mL 17.463 mL 34.926 mL 69.8519 mL 87.3149 mL
5 mM 0.6985 mL 3.4926 mL 6.9852 mL 13.9704 mL 17.463 mL
10 mM 0.3493 mL 1.7463 mL 3.4926 mL 6.9852 mL 8.7315 mL
50 mM 0.0699 mL 0.3493 mL 0.6985 mL 1.397 mL 1.7463 mL
100 mM 0.0349 mL 0.1746 mL 0.3493 mL 0.6985 mL 0.8731 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Tupichinol A

New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity.[Pubmed:12608845]

J Nat Prod. 2003 Feb;66(2):161-8.

Seven new compounds, including three new flavans [Tupichinol A-C (1-3)], three new spirostanol sapogenins [tupichigenin D-F (4-6)], and one new pregnane genin [tupipregnenolone (7)], together with 18 known compounds, were isolated from the underground parts of Tupistra chinensis. The structures of the new compounds were elucidated by spectroscopic analysis and chemical evidence. The structures and relative stereochemistry of 1 and 9 were further confirmed by single-crystal X-ray crystallographic analysis. Compounds Delta(25(27))-pentrogenin, 10, and ranmogenin A showed 100%, 96%, and 80% inhibition, respectively, against human gastric tumor (NUGC) cells at a concentration of 50 microM. Delta(25(27))-pentrogenin showed 100% inhibition against human nasopharyngeal carcinoma (HONE-1) cells at a concentration of 50 microM.

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