Cancer Research

Cancer is a term used to define a group of diseases in which abnormal cells divide without control, are able to invade neighboring tissues/organs and metastasize. Cancer has been characterized by six hallmarks; self sufficiency in proliferative growth signals, insensitivity to growth inhibitors, evasion of apoptosis, limitless replicative potential, ability to develop blood vessels (angiogenesis), and tissue invasion and metastasis.

Cancer Research Products Areas

Products for Cancer Research - Page 11

Cat.No. Product Name Information/Activity
BCC1306 3,3'-Diindolylmethane 3,3'-Diindolylmethane is a strong, pure androgen receptor (AR) antagonist.
BCC4497 Erastin Erastin is a ferroptosis inducer. Erastin binds and inhibits voltage-dependent anion channels (VDAC2/VDAC3).
BCC2323 Ferrostatin-1 (Fer-1) Ferrostatin-1 is a potent inhibitor of ferroptosis with an EC50 of 60 nM.
BCC2401 GRI 977143 Selective LPA<sub>2</sub> agonist; antiapoptotic
BCC2402 Mdivi 1 Mdivi-1 is a selective dynamin-related protein 1 (Drp1) inhibitor. Mdivi-1 is a mitochondrial division/mitophagy inhibitor.
BCC2403 Melphalan Melphalan is an effective DNA alkylating agent, with potent antitumor activity.
BCC3714 3-Methyladenine 3-Methyladenine is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K.
BCC2247 Necrostatin-1 Necrostatin-1 (Nec-1) is a potent necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase (EC50=182 nM). Necrostatin-1 is also an IDO inhibitor.
BCC7992 Necrosulfonamide (E)-Necrosulfonamide is a necroptosis inhibitor acting by selectively targeting the mixed lineage kinase domain-like protein (MLKL) to block the necrosome formation.
BCC2405 TLQP 21 869988-94-3