Metastasis
Metastasis is the spread of cancer from the primary neoplasm (tumor) to distant organs. As primary tumors can often be removed by surgery and radiation it is metastases that contribute to the majority of morbidity and mortality associated with cancer.
Metastasis Products Targets
Products for Metastasis - Page 5
- Cat.No. Product Name Information/Activity
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BCC3826
Nocodazole
Nocodazole is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells. Nocodazole inhibits Bcr-Abl, and activates CRISPR/Cas9.
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BCC3819
Noscapine HCl
Bradykinin antagonist. Also tubulin inhibitor
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BCN4650
Paclitaxel
Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.
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BCN2292
Vinblastine Sulfate
Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.
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BCN2542
Vincristine sulfate
Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
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BCN2288
Vinorelbine Tartrate
Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
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BCC7568
XRP44X
729605-21-4
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BCC4375
(-)-Blebbistatin
(-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II.
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BCC7195
(R)-(+)-Blebbistatin
(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective inhibitor of myosin II ATPase.
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BCC7169
(±)-Blebbistatin
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function.
