Metastasis

Metastasis is the spread of cancer from the primary neoplasm (tumor) to distant organs. As primary tumors can often be removed by surgery and radiation it is metastases that contribute to the majority of morbidity and mortality associated with cancer.

Metastasis Products Targets

Products for Metastasis - Page 6

Cat.No. Product Name Information/Activity
BCC5425 BTS BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility.
BCC3944 A 205804 A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases.
BCC3946 A 286982 Potent inhibitor of the LFA-1/ICAM-1 interaction
BCC5826 Ac2-12 256447-08-2
BCC5825 Ac2-26 Ac2-26, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. Ac2-26 also decreases AnxA1 protein expression, inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue.
BCC3945 BIO 1211 Selective α4β1 (VLA-4) inhibitor
BCC8002 BIO 5192 327613-57-0
BCC3942 Cilengitide Cilengitide, a cyclic RGD-containing peptide, is a potent and selective integrin inhibitor for αvβ3 and αvβ5 receptor, with IC50s of 4 and 79 nM, respectively.
BCC5988 Echistatin, α1 isoform 154303-05-6
BCC6998 GR 144053 trihydrochloride 1215333-48-4