Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 24

  1. Cat.No. Product Name Information/Activity
  2. BCC5096 Tolvaptan Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. Tolvaptan chemical structure
  3. BCC5932 Bay 55-9837 463930-25-8 Bay 55-9837 chemical structure
  4. BCC5725 VIP (guinea pig) 96886-24-7 VIP (guinea pig) chemical structure
  5. BCC5754 [Ala11,22,28]VIP 291524-04-4 [Ala11,22,28]VIP chemical structure
  6. BCC5719 [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) 93965-89-0 [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) chemical structure
  7. BCC5838 VIP (6-28) (human, rat, porcine, bovine) VIP(6-28)(human, rat, porcine, bovine) is an effective antagonist of the actions of exogenous vasoactive intestinal peptide (<b>VIP</b>) on cAMP. VIP (6-28) (human, rat, porcine, bovine) chemical structure
  8. BCC5968 [D-p-Cl-Phe6,Leu17]-VIP 102805-45-8 [D-p-Cl-Phe6,Leu17]-VIP chemical structure
  9. BCC7993 BCH LAT1-IN-1 (BCH) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis. BCH chemical structure
  10. BCC6032 N2-Methyl-L-arginine 2480-28-6 N2-Methyl-L-arginine chemical structure
  11. BCN4126 Phlorizin Phlorizin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin chemical structure

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