Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 20

  1. Cat.No. Product Name Information/Activity
  2. BCC3950 Thrombin Receptor Agonist Peptide Sfllrnpndkyepf is a synthetic thrombin receptor agonist peptide. Thrombin Receptor Agonist Peptide chemical structure
  3. BCC3957 TRAP-6 TRAP-6 (PAR-1 agonist peptide) is a protease-activated receptor 1 (PAR1) agonist. TRAP-6 chemical structure
  4. BCC3953 VKGILS-NH2 Control peptide for SLIGKV-NH<sub>2</sub> VKGILS-NH2 chemical structure
  5. BCC7734 FR 171113 173904-50-2 FR 171113 chemical structure
  6. BCC6279 FSLLRY-NH2 245329-02-6 FSLLRY-NH2 chemical structure
  7. BCC7433 RWJ 56110 252889-88-6 RWJ 56110 chemical structure
  8. BCC7125 SCH 79797 dihydrochloride SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 dihydrochloride inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride inhibits thrombin-induced platelet aggregation with an IC50 of 3 μM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 dihydrochloride also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes. SCH 79797 dihydrochloride chemical structure
  9. BCC5770 tcY-NH2 327177-34-4 tcY-NH2 chemical structure
  10. BCC6281 Q94 hydrochloride 1052076-77-3 Q94 hydrochloride chemical structure
  11. BCC7392 APC 366 Tryptase inhibitor APC 366 chemical structure

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