Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 23

  1. Cat.No. Product Name Information/Activity
  2. BCC6257 SB 611812 345892-71-9 SB 611812 chemical structure
  3. BCC7713 SB 657510 SB-657510 is a selective urotensin II (UII) receptor (UT) antagonist. The Ki values are 61, 17, 30, 65 and 56 nM for human, monkey, cat, rat and mouse receptors, respectively. SB-657510 exerts anti-inflammatory effects by inhibiting UII-induced upregulation of inflammatory mediators such as adhesion molecules, cytokines, and tissue factor in human vascular endothelial cells. SB 657510 chemical structure
  4. BCC6256 SB 706375 733734-61-7 SB 706375 chemical structure
  5. BCC5917 UFP 803 879497-82-2 UFP 803 chemical structure
  6. BCC5985 [Orn5]-URP 782485-03-4 [Orn5]-URP chemical structure
  7. BCC1525 Desmopressin Synthetic vasopressin analog; V<sub>1B</sub> and V<sub>2</sub> agonist,Desmopressin(DDAVP) is the synthetic analogue of the antidiuretic hormone arginine vasopressin. Desmopressin chemical structure
  8. BCC5981 d[Leu4,Lys8]-VP 42061-33-6 d[Leu4,Lys8]-VP chemical structure
  9. BCC6011 (d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin 73168-24-8 (d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin chemical structure
  10. BCC7812 OPC 21268 Fuscoside (OPC-21268) is an orally effective, nonpeptide, vasopressin V1 receptor antagonist with an IC50 of 0.4 μM. OPC 21268 chemical structure
  11. BCC7324 SR 49059 150375-75-0 SR 49059 chemical structure

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