Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 13

  1. Cat.No. Product Name Information/Activity
  2. BCC7079 Suramin hexasodium salt Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM). Suramin sodium salt is an antitrypanosomal, anti-neoplastic and anti-angiogenic agent. Suramin hexasodium salt chemical structure
  3. BCC4973 Ticlopidine HCl Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM. Ticlopidine HCl chemical structure
  4. BCC7151 PIT 56583-49-4 PIT chemical structure
  5. BCC7570 UDP disodium salt Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52) and a potent P2Y14 antagonist (pEC50=7.28). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis. UDP disodium salt chemical structure
  6. BCC2306 Anagrelide HCl Anagrelide hydrochloride (BL4162A) is a drug used for the treatment of essential thrombocytosis. Anagrelide HCl chemical structure
  7. BCC7940 BC 11-38 686770-80-9 BC 11-38 chemical structure
  8. BCN5807 Caffeine 58-08-2 Caffeine chemical structure
  9. BCC6173 Carbazeran citrate 153473-94-0 Carbazeran citrate chemical structure
  10. BCC7814 CDP 840 hydrochloride Potent and selective PDE4 inhibitor CDP 840 hydrochloride chemical structure
  11. BCC7338 CGH 2466 dihydrochloride Anti-inflammatory agent. Inhibitor of PDE4 and p38 MAPK, also adenosine receptor antagonist CGH 2466 dihydrochloride chemical structure

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