Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 7

  1. Cat.No. Product Name Information/Activity
  2. BCC7244 Cinalukast 128312-51-6 Cinalukast chemical structure
  3. BCC7310 FPL 55712 40785-97-5 FPL 55712 chemical structure
  4. BCC7334 MK 571 MRP1 inhibitor; also CysLT<sub>1</sub> (LTD<sub>4</sub>) inverse agonist MK 571 chemical structure
  5. BCC4680 Montelukast Sodium Montelukast (sodium) (MK0476) is a potent, selective CysLT1 receptor antagonist. Montelukast Sodium chemical structure
  6. BCC4827 Pranlukast Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively. Pranlukast chemical structure
  7. BCC7180 SR 2640 hydrochloride 146662-42-2 SR 2640 hydrochloride chemical structure
  8. BCC6274 Gue 1654 397290-30-1 Gue 1654 chemical structure
  9. BCN2215 Arachidonic acid Arachidonic acid is an essential fatty acid and a major constituent of biomembranes. Arachidonic acid chemical structure
  10. BCC6038 BAY-X 1005 Veliflapon (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. Veliflapon inhibits the synthesis of the leukotrienes B4 and C4. BAY-X 1005 chemical structure
  11. BCC7457 Cilastatin sodium 81129-83-1 Cilastatin sodium chemical structure

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