Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 8

  1. Cat.No. Product Name Information/Activity
  2. BCC7017 MK 886 MK886 is a potent 5-lipoxygenase activating protein inhibitor (FLAP) also a non-competitive inhibitor of PPAR alpha. a potent inhibitor of leukotriene (LT) biosynthesis in intact human polymorphonuclear leukocytes with IC 50 of 2.5 nM. Block the synthessis of leukotrien intact activate leukocyte. MK 886 chemical structure
  3. BCC6717 17-ODYA Alkynyl Stearic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. 17-ODYA chemical structure
  4. BCN5599 Baicalein Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 mM. Baicalein chemical structure
  5. BCC7013 BW-B 70C 5-Lipoxygenase inhibitor BW-B 70C chemical structure
  6. BCC7504 PD 146176 PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis. PD 146176 chemical structure
  7. BCC7288 STEARDA 105955-10-0 STEARDA chemical structure
  8. BCC6735 2-TEDC 132465-10-2 2-TEDC chemical structure
  9. BCC2515 Zileuton Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Zileuton chemical structure
  10. BCN2203 Corticosterone Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. Corticosterone chemical structure
  11. BCC4395 Benidipine HCl Benidipine hydrochloride is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). Benidipine HCl chemical structure

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