Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 10

  1. Cat.No. Product Name Information/Activity
  2. BCC5847 Neuromedin U (rat) Neuromedin U, rat is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception. Neuromedin U (rat) chemical structure
  3. BCC1119 Bumetanide Bumetanide (Ro 10-6338;PF 1593) is a selective Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively. Bumetanide chemical structure
  4. BCC3782 Furosemide Furosemide is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema. Furosemide chemical structure
  5. BCC5160 ATP disodium salt ATP disodium salt is a phosphate-group donor for substrate activation in metabolic reactions and the coenzyme for a large number of kinases. ATP disodium salt chemical structure
  6. BCC7855 ATPγS tetralithium salt 93839-89-5 ATPγS tetralithium salt chemical structure
  7. BCC7643 BzATP triethylammonium salt 112898-15-4 BzATP triethylammonium salt chemical structure
  8. BCC7603 alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt α,β-Methylene ATP trisodium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand. alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt chemical structure
  9. BCC5794 2-Methylthioadenosine diphosphate trisodium salt 475193-31-8 2-Methylthioadenosine diphosphate trisodium salt chemical structure
  10. BCC6918 2-Methylthioadenosine triphosphate tetrasodium salt 100020-57-3 2-Methylthioadenosine triphosphate tetrasodium salt chemical structure
  11. BCC5879 MRS 2365 436847-09-5 MRS 2365 chemical structure

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