Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 2

  1. Cat.No. Product Name Information/Activity
  2. BCC5910 Apelin-36 (human) 252642-12-9 Apelin-36 (human) chemical structure
  3. BCC5911 Apelin-36 (rat, mouse) 230299-95-3 Apelin-36 (rat, mouse) chemical structure
  4. BCC6278 ML 221 ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays. ML 221 chemical structure
  5. BCC5904 Bombinakinin M 509151-65-9 Bombinakinin M chemical structure
  6. BCC5996 Sar-[D-Phe8]-des-Arg9-Bradykinin 126959-88-4 Sar-[D-Phe8]-des-Arg9-Bradykinin chemical structure
  7. BCC5995 [Phe8Ψ(CH-NH)-Arg9]-Bradykinin 118122-39-7 [Phe8Ψ(CH-NH)-Arg9]-Bradykinin chemical structure
  8. BCC5993 Lys-Bradykinin 342-10-9 Lys-Bradykinin chemical structure
  9. BCC5991 Lys-[Des-Arg9]Bradykinin 71800-36-7 Lys-[Des-Arg9]Bradykinin chemical structure
  10. BCC5964 HOE 140 Icatibant (HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively. HOE 140 chemical structure
  11. BCC6094 MEN 11270 235082-52-7 MEN 11270 chemical structure

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