Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 54

  1. Cat.No. Product Name Information/Activity
  2. BCC7490 Alprenolol hydrochloride Alprenolol (hydrochloride) is a non-selective beta blocker as well as 5-HT1A receptor antagonist. Alprenolol hydrochloride chemical structure
  3. BCC6880 Cyanopindolol hemifumarate 69906-86-1 Cyanopindolol hemifumarate chemical structure
  4. BCC6854 MM 77 dihydrochloride 159187-70-9 MM 77 dihydrochloride chemical structure
  5. BCC6003 NAD 299 hydrochloride 184674-99-5 NAD 299 hydrochloride chemical structure
  6. BCC6693 NAN-190 hydrobromide NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A. NAN-190 hydrobromide chemical structure
  7. BCC7098 SDZ 21009 39731-05-0 SDZ 21009 chemical structure
  8. BCC6993 (S)-WAY 100135 dihydrochloride Potent, selective 5-HT<sub>1A</sub> antagonist (S)-WAY 100135 dihydrochloride chemical structure
  9. BCC2054 WAY-100635 maleate salt WAY-100635 maleate salt is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 maleate salt has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate salt is also a potent dopamine D4 receptor agonist. WAY-100635 maleate salt chemical structure
  10. BCC6637 MDL 72832 hydrochloride Potent 5-HT<sub>1A</sub> ligand MDL 72832 hydrochloride chemical structure
  11. BCC6732 CGS 12066B dimaleate 109028-10-6 CGS 12066B dimaleate chemical structure

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