Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 52

  1. Cat.No. Product Name Information/Activity
  2. BCC6770 3-Bromo-7-nitroindazole 3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or inducible nitric oxide synthase (iNOS). 3-Bromo-7-nitroindazole affects the intercellular messenger nitric oxide (NO) synthesis throughout the body and brain. 3-Bromo-7-nitroindazole chemical structure
  3. BCC5644 Pentamidine isethionate Pentamidine isethionate (MP-601205 isethionate) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine isethionate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine isethionate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine isethionate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. Pentamidine isethionate chemical structure
  4. BCC6965 Nω-Propyl-L-arginine hydrochloride 137361-05-8 Nω-Propyl-L-arginine hydrochloride chemical structure
  5. BCC6762 N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide 142867-52-5 N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide chemical structure
  6. BCN2691 L-Arginine L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. L-Arginine chemical structure
  7. BCC5004 Nicorandil Nicorandil (SG-75) is potassium channel activator. Nicorandil chemical structure
  8. BCC5670 SIN-1 chloride 16142-27-1 SIN-1 chloride chemical structure
  9. BCC6712 SNAP 79032-48-7 SNAP chemical structure
  10. BCC6714 SNOG 57564-91-7 SNOG chemical structure
  11. BCC6950 Spermine NONOate Slow NO releasing agent Spermine NONOate chemical structure

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