Asthma Research

Asthma is a common chronic inflammatory disease of the respiratory system that affects approximately 22 million people in US. It has been classified as a complex genetic condition that is determined by the interaction of numerous genes along with environmental factors.

Asthma Research Products Targets

Products for Asthma Research - Page 7

Cat.No. Product Name Information/Activity
BCC7161 2-Chloro-N6-cyclopentyladenosine Potent, selective A<sub>1</sub> agonist
BCC7160 N6-Cyclopentyladenosine N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively.
BCC7716 (±)-5'-Chloro-5'-deoxy-ENBA Highly selective A<sub>1</sub> agonist
BCC7215 GR 79236 GR79236 is a highly potent and selective adenosine A1 receptor agonist (Ki = 3.1 nM) that has analgesic and anti-inflammatory actions in humans and animals.
BCC7311 2'-MeCCPA 205171-12-6
BCC7374 SDZ WAG 994 130714-47-5
BCC6664 1,3-Dipropyl-8-phenylxanthine 85872-53-3
BCC6649 DPCPX 102146-07-6
BCC6124 KW 3902 Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment. Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 (CYP450). Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases.
BCC7240 PSB 36 524944-72-7