Asthma Research
Asthma is a common chronic inflammatory disease of the respiratory system that affects approximately 22 million people in US. It has been classified as a complex genetic condition that is determined by the interaction of numerous genes along with environmental factors.
Asthma Research Products Targets
- Adenosine A2B Receptor (7)
- Adenosine A2A Receptor (11)
- Matrix Metalloprotease (16)
- Caspase (9)
- Elastase (1)
- Lipoxygenase (8)
- Leukotriene and Related Receptor (13)
- Bradykinin Receptor (12)
- Cytokine Receptor (4)
- Urokinase (2)
- Deubiquitinating Enzyme (12)
- Aminopeptidase (5)
- Angiotensin-Converting Enzyme (8)
- Carboxypeptidase (1)
- Calpain (7)
- Histamine H4 Receptor (12)
- Histamine H3 Receptor (22)
- Histamine H2 Receptor (10)
- Histamine H1 Receptor (17)
- Adenosine A3 Receptor (8)
- Adenosine A1 Receptor (12)
- IαB Kinase (6)
- Calcium-Activated Potassium (KCa) Channel (19)
- Dipeptidyl Peptidase IV (1)
- Cathepsin (9)
- gamma-Secretase (9)
- ADAMs (1)
- Proteasome (5)
Products for Asthma Research - Page 5
- Cat.No. Product Name Information/Activity
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BCC2473
TPCA-1
TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM. TPCA-1 is an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation.
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BCC7576
BAY-u 9773
Dual CysLT<sub>1</sub> and CysLT<sub>2</sub> antagonist
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BCC7244
Cinalukast
128312-51-6
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BCC7310
FPL 55712
40785-97-5
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BCC7334
MK 571
MRP1 inhibitor; also CysLT<sub>1</sub> (LTD<sub>4</sub>) inverse agonist
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BCC4680
Montelukast Sodium
Montelukast (sodium) (MK0476) is a potent, selective CysLT1 receptor antagonist.
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BCC4827
Pranlukast
Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively.
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BCC7180
SR 2640 hydrochloride
146662-42-2
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BCC6274
Gue 1654
397290-30-1
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BCN2215
Arachidonic acid
Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.
