Asthma Research

Asthma is a common chronic inflammatory disease of the respiratory system that affects approximately 22 million people in US. It has been classified as a complex genetic condition that is determined by the interaction of numerous genes along with environmental factors.

Asthma Research Products Targets

Products for Asthma Research - Page 2

Cat.No. Product Name Information/Activity
BCC6914 WIN 64338 hydrochloride Bradykinin B<sub>2</sub> antagonist
BCC5903 Bombinakinin-GAP 573671-91-7
BCC7984 MaxiPost Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo.
BCC7448 BMS 191011 BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models.
BCC7526 CyPPA 73029-73-9
BCC7060 DCEBIO DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl－ secretion in T84 colonic cells. DCEBIO stimulates Cl－ secretion via the activation of hIK1 K＋ channels and the activation of an apical membrane Cl－ conductance.
BCC6904 1-EBIO 10045-45-1
BCC7914 GW 542573X 660846-41-3
BCC7779 NS 1619 NS-1619 is a selective large conductance Ca2+-activated K+-channel activator.
BCC1809 NS309 NS309 is a positive modulator of small- and intermediate- conductance Ca2+-activated K+ channels (KCa2 and KCa3.1 channels); increases Ca2+ sensitivity. Displays no activity at BK channels.