Addiction Research

According to the World Health Organization (WHO), addiction is 'a chronic disease of the central nervous system that is characterized by a loss of control over impulsive behavior that leads to compulsive drug seeking and taking, and to relapses even after months of abstinence'. Addiction is a complex neuroadaptive process, where drugs of abuse alter cellular and molecular aspects of neural function. The brain circuits mediating the various behavioral effects of these drugs are rendered more, or less, responsive to those effects.

Addiction Research Products Targets

Products for Addiction Research - Page 19

Cat.No. Product Name Information/Activity
BCC7837 NPEC-caged-dopamine 1257326-23-0
BCC6848 SKF 38393 hydrobromide 20012-10-6
BCC7144 SKF 77434 hydrobromide 300561-58-4
BCC7071 SKF 81297 hydrobromide 67287-39-2
BCC7252 SKF 83822 hydrobromide 74115-10-9
BCC7251 SKF 83959 hydrobromide 67287-95-0
BCC7148 LE 300 274694-98-3
BCC6849 SCH 23390 hydrochloride SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT2 and 5-HT1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM.
BCC7317 SCH 39166 hydrobromide 1227675-51-5
BCC7121 SKF 83566 hydrobromide 108179-91-5