Addiction Research

According to the World Health Organization (WHO), addiction is 'a chronic disease of the central nervous system that is characterized by a loss of control over impulsive behavior that leads to compulsive drug seeking and taking, and to relapses even after months of abstinence'. Addiction is a complex neuroadaptive process, where drugs of abuse alter cellular and molecular aspects of neural function. The brain circuits mediating the various behavioral effects of these drugs are rendered more, or less, responsive to those effects.

Addiction Research Products Targets

Products for Addiction Research - Page 48

Cat.No. Product Name Information/Activity
BCC6614 nor-Binaltorphimine dihydrochloride Norbinaltorphimine dihydrochloride is a potent and selective κ opioid receptor antagonist.
BCC6799 DIPPA hydrochloride 155512-52-0
BCC7003 GNTI dihydrochloride 351183-88-5
BCC6308 ML 190 1355244-02-8
BCC6958 DAMGO DAMGO is a μ-opioid receptor (μ-OPR ) selective agonist with a Kd of 3.46 nM for native μ-OPR.
BCC1008 Endomorphin-1 Endomorphin 1, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
BCC5697 Endomorphin-2 Endomorphin 2, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
BCC6000 Fentanyl citrate 990-73-8
BCC4920 Meptazinol HCl Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM.
BCC6090 Oxycodone hydrochloride 124-90-3