Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 42

  1. Cat.No. Product Name Information/Activity
  2. BCC7292 N20C hydrochloride 1177583-87-7 N20C hydrochloride chemical structure
  3. BCC2676 H-D-Ser-OH (R)-Serine, an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. (R)-Serine has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration. H-D-Ser-OH chemical structure
  4. BCC6864 Spermine tetrahydrochloride Spermine tetrahydrochloride is an endogenous metabolite. Spermine tetrahydrochloride chemical structure
  5. BCC6590 (1S,3R)-ACPD 111900-32-4 (1S,3R)-ACPD chemical structure
  6. BCC6567 (±)-trans-ACPD trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. (±)-trans-ACPD chemical structure
  7. BCC6910 CHPG CHPG is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. CHPG protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways. CHPG chemical structure
  8. BCC7755 CHPG Sodium salt CHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. CHPG sodium salt protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways.. CHPG Sodium salt chemical structure
  9. BCC6613 (RS)-3,5-DHPG 19641-83-9 (RS)-3,5-DHPG chemical structure
  10. BCC6802 (S)-3,5-DHPG 162870-29-3 (S)-3,5-DHPG chemical structure
  11. BCC6604 (RS)-3-Hydroxyphenylglycine 31932-87-3 (RS)-3-Hydroxyphenylglycine chemical structure

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