Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 35

  1. Cat.No. Product Name Information/Activity
  2. BCC4590 NMDA (N-Methyl-D-aspartic acid) NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. NMDA (N-Methyl-D-aspartic acid) chemical structure
  3. BCC6573 Quinolinic acid Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction. Quinolinic acid chemical structure
  4. BCC6865 Spermidine trihydrochloride Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents. Spermidine trihydrochloride chemical structure
  5. BCC6599 (RS)-(Tetrazol-5-yl)glycine (RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is a highly potent and selective N-methyl-D-aspartate (NMDA) receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D and GluN1/GluN2A, respectively. (RS)-(Tetrazol-5-yl)glycine induces seizure responses and Fos in mice. (RS)-(Tetrazol-5-yl)glycine chemical structure
  6. BCC6584 ACBC 22264-50-2 ACBC chemical structure
  7. BCC7753 DL-AP5 Sodium salt 1303993-72-7 DL-AP5 Sodium salt chemical structure
  8. BCC6553 D-AP5 D-AP5 is a NMDA receptor antagonist. D-AP5 chemical structure
  9. BCC6552 DL-AP5 76326-31-3 DL-AP5 chemical structure
  10. BCC6554 L-AP5 79055-67-7 L-AP5 chemical structure
  11. BCC6551 DL-AP7 78966-69-5 DL-AP7 chemical structure

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