Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 31

  1. Cat.No. Product Name Information/Activity
  2. BCC5785 pep2-SVKE 1315378-76-7 pep2-SVKE chemical structure
  3. BCC5783 pep4c 243843-43-8 pep4c chemical structure
  4. BCC4824 Piracetam Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. Piracetam chemical structure
  5. BCC6940 ATPA ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively. ATPA chemical structure
  6. BCC6586 Domoic acid 14277-97-5 Domoic acid chemical structure
  7. BCC6597 (S)-(-)-5-Iodowillardiine 140187-25-3 (S)-(-)-5-Iodowillardiine chemical structure
  8. BCC6572 Kainic acid Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. Kainic acid chemical structure
  9. BCC7297 MNI caged kainic acid 1315378-75-6 MNI caged kainic acid chemical structure
  10. BCC6840 SYM 2081 SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. SYM 2081 chemical structure
  11. BCC7462 ACET 936095-50-0 ACET chemical structure

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