Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 32

  1. Cat.No. Product Name Information/Activity
  2. BCC7275 NS 3763 70553-45-6 NS 3763 chemical structure
  3. BCC2314 Topiramate Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase. Topiramate chemical structure
  4. BCC7255 UBP 296 745055-86-1 UBP 296 chemical structure
  5. BCC7172 UBP 301 569371-10-4 UBP 301 chemical structure
  6. BCC7256 UBP 302 UBP 302 is a potent and selective GLUK5-subunit containing kainate receptor antagonist (apparent Kd=402 nM), and displays very little affinity on GluK2 (GluR6) kainate receptors. Anxiolytic effects. UBP 302 chemical structure
  7. BCC6052 UBP 310 902464-46-4 UBP 310 chemical structure
  8. BCN6291 Arctigenin Arctigenin is a lignan found in certain plants of the Asteraceae; it has shown antiviral and anticancer effects in glass; it is the aglycone of arctiin. Arctigenin chemical structure
  9. BCC5883 PDZ1 Domain inhibitor peptide 1315378-73-4 PDZ1 Domain inhibitor peptide chemical structure
  10. BCC7995 2-MPPA 254737-29-6 2-MPPA chemical structure
  11. BCC1327 Acamprosate calcium Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction. Acamprosate calcium chemical structure

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