Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 28

  1. Cat.No. Product Name Information/Activity
  2. BCC6815 Evans Blue tetrasodium salt Selective P2X purinergic antagonist,Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue tetrasodium salt chemical structure
  3. BCC7566 GYKI 47261 dihydrochloride 1217049-32-5 GYKI 47261 dihydrochloride chemical structure
  4. BCC7072 GYKI 52466 dihydrochloride 102771-26-6 GYKI 52466 dihydrochloride chemical structure
  5. BCC7407 GYKI 53655 hydrochloride GYKI53655 hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist. GYKI 53655 hydrochloride chemical structure
  6. BCC7885 IEM 1925 dihydrobromide 258282-23-4 IEM 1925 dihydrobromide chemical structure
  7. BCC7476 Naspm trihydrochloride Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. Naspm trihydrochloride chemical structure
  8. BCC6624 NBQX NBQX is a highly selective and competitive AMPA receptor antagonist. NBQX chemical structure
  9. BCC6907 NBQX disodium salt 479347-86-9 NBQX disodium salt chemical structure
  10. BCC7478 Philanthotoxin 74 Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. Philanthotoxin 74 chemical structure
  11. BCC6866 SYM 2206 SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist. SYM 2206 chemical structure

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