Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 41

  1. Cat.No. Product Name Information/Activity
  2. BCC1939 SDZ 220-581 SDZ 220-581 is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7. SDZ 220-581 chemical structure
  3. BCC6730 Synthalin sulfate 182285-12-7 Synthalin sulfate chemical structure
  4. BCC6122 TCN 201 852918-02-6 TCN 201 chemical structure
  5. BCC6123 TCN 213 556803-08-8 TCN 213 chemical structure
  6. BCC6111 TCN 237 dihydrochloride NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor. TCN 237 dihydrochloride chemical structure
  7. BCC7482 TCS 46b 302799-86-6 TCS 46b chemical structure
  8. BCC6984 CCMQ 132623-44-0 CCMQ chemical structure
  9. BCC7862 CIQ CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. CIQ chemical structure
  10. BCC2946 H-Gly-OH Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. H-Gly-OH chemical structure
  11. BCC5888 MNI-caged-NMDA 1227675-52-6 MNI-caged-NMDA chemical structure

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