Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.
Multiple Sclerosis Products Targets
- STAT (10)
- Voltage-gated Potassium (KV) Channel (38)
- Integrin Receptor (15)
- Others (29)
- Complement (2)
- Vitamin D Receptor (10)
- PORCN (4)
- beta-catenin (13)
- Casein Kinase 1 (7)
- AMPA Receptor (45)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- NMDA Receptor (87)
- Kainate Receptor (22)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- TRPM (8)
- Tankyrase (5)
- ROS and Other Gaseous Donor (8)
- Nrf2 (5)
- ITK (2)
- ASK1 (2)
- Acid-Sensing Ion Channel (3)
- Calcium-Activated Potassium (KCa) Channel (19)
- Inward Rectifier Potassium (Kir) Channel (21)
- NCX (5)
- Retinoid X Receptor (13)
- Cytokine (15)
Products for Multiple Sclerosis - Page 10
- Cat.No. Product Name Information/Activity
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BCC6126
VU 591 hydrochloride
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM.
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BCC3944
A 205804
A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases.
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BCC3946
A 286982
Potent inhibitor of the LFA-1/ICAM-1 interaction
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BCC3945
BIO 1211
Selective <span class='symbol'>α</span><sub>4</sub><span class='symbol'>β</span><sub>1</sub> (VLA-4) inhibitor
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BCC8002
BIO 5192
327613-57-0
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BCC3942
Cilengitide
Cilengitide, a cyclic RGD-containing peptide, is a potent and selective integrin inhibitor for αvβ3 and αvβ5 receptor, with IC50s of 4 and 79 nM, respectively.
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BCC5988
Echistatin, α1 isoform
154303-05-6
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BCC6998
GR 144053 trihydrochloride
1215333-48-4
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BCC3943
MNS
MNS is a potent and selective inhibitor of Src and Syk tyrosine kinases.
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BCC6275
P11
848644-86-0


