Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.

Multiple Sclerosis Products Targets

Products for Multiple Sclerosis - Page 10

  1. Cat.No. Product Name Information/Activity
  2. BCC6126 VU 591 hydrochloride VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU 591 hydrochloride chemical structure
  3. BCC3944 A 205804 A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases. A 205804 chemical structure
  4. BCC3946 A 286982 Potent inhibitor of the LFA-1/ICAM-1 interaction A 286982 chemical structure
  5. BCC3945 BIO 1211 Selective <span class='symbol'>&#945;</span><sub>4</sub><span class='symbol'>&#946;</span><sub>1</sub> (VLA-4) inhibitor BIO 1211 chemical structure
  6. BCC8002 BIO 5192 327613-57-0 BIO 5192 chemical structure
  7. BCC3942 Cilengitide Cilengitide, a cyclic RGD-containing peptide, is a potent and selective integrin inhibitor for αvβ3 and αvβ5 receptor, with IC50s of 4 and 79 nM, respectively. Cilengitide chemical structure
  8. BCC5988 Echistatin, α1 isoform 154303-05-6 Echistatin, α1 isoform chemical structure
  9. BCC6998 GR 144053 trihydrochloride 1215333-48-4 GR 144053 trihydrochloride chemical structure
  10. BCC3943 MNS MNS is a potent and selective inhibitor of Src and Syk tyrosine kinases. MNS chemical structure
  11. BCC6275 P11 848644-86-0 P11 chemical structure

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