Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.

Multiple Sclerosis Products Targets

Products for Multiple Sclerosis - Page 13

Cat.No. Product Name Information/Activity
BCC5108 CORM-3 CORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. CORM-3 reduces NLRP3 inflammasome activation.
BCC5670 SIN-1 chloride 16142-27-1
BCC6712 SNAP 79032-48-7
BCC6714 SNOG 57564-91-7
BCC6950 Spermine NONOate Slow NO releasing agent
BCC3737 Bexarotene Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.
BCC7637 CD 3254 CD3254 a potent and selective retinoid-X-receptor (RXR) agonist.
BCC6110 Fluorobexarotene Fluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
BCC2284 Isotretinoin Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne.
BCN2185 Retinoic acid Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.