Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.

Multiple Sclerosis Products Targets

Products for Multiple Sclerosis - Page 20

Cat.No. Product Name Information/Activity
BCC7182 E-4031 dihydrochloride E-4031 is a class III antiarrhythmic agent which selectively blocks hERG potassium channel.
BCC7806 JNJ 303 JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).
BCC1682 KN-92 phosphate KN-92 phosphate is an inactive derivative of KN-93.
BCC1683 KN-93 CaM kinase II inhibitor; also K+ channel blocker (KV),KN-93 is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.
BCC7231 Linopirdine dihydrochloride 113168-57-3
BCC7709 Margatoxin Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research.
BCC6255 ProTx I 484598-35-8
BCC7927 Psora 4 Potent KV1.3 channel blocker
BCC6044 RuBi-4AP 851956-02-0
BCC5990 ShK-Dap22 220384-25-8