Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.

Multiple Sclerosis Products Targets

Products for Multiple Sclerosis - Page 26

Cat.No. Product Name Information/Activity
BCC8077 SB 225002 SB225002, a potent, selective and non-peptide CXCR2 antagonist, inhibits 125I-IL-8 binding to CXCR2 with an IC50 of 22 nM.
BCC5936 SB 265610 SB-265610 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s of 3.7 nM and 70 nM, respectively.
BCC7910 TC 14012 368874-34-4
BCC4448 WZ811 WZ811 is an orally active, highly potent competitive antagonist of CXCR4. WZ811 efficiently inhibits CXCR4/SDF-1 (or CXCL12)-mediated modulation of cAMP levels (EC50=1.2 nM) and SDF-1 induced Matrigel invasion in cells (EC50=5.2 nM).
BCC6926 (RS)-AMPA hydrobromide 171259-81-7
BCC6582 (R)-AMPA 83654-13-1
BCC6560 (RS)-AMPA 74341-63-2
BCC6583 (S)-AMPA 83643-88-3
BCC7147 Cl-HIBO 909400-43-7
BCC7106 (S)-CPW 399 389888-02-2