Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.
Multiple Sclerosis Products Targets
- STAT (10)
- Voltage-gated Potassium (KV) Channel (38)
- Integrin Receptor (15)
- Others (29)
- Complement (2)
- Vitamin D Receptor (10)
- PORCN (4)
- beta-catenin (13)
- Casein Kinase 1 (7)
- AMPA Receptor (45)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- NMDA Receptor (87)
- Kainate Receptor (22)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- TRPM (8)
- Tankyrase (5)
- ROS and Other Gaseous Donor (8)
- Nrf2 (5)
- ITK (2)
- ASK1 (2)
- Acid-Sensing Ion Channel (3)
- Calcium-Activated Potassium (KCa) Channel (19)
- Inward Rectifier Potassium (Kir) Channel (21)
- NCX (5)
- Retinoid X Receptor (13)
- Cytokine (15)
Products for Multiple Sclerosis - Page 34
- Cat.No. Product Name Information/Activity
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BCC6554
L-AP5
79055-67-7
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BCC6551
DL-AP7
78966-69-5
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BCC6631
Arcaine sulfate
14923-17-2
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BCC6602
(R)-4-Carboxyphenylglycine
134052-68-9
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BCC7078
CGP 37849
CGP 37849 is a potent, competitive and orally active N-methyl-D-aspartate (NMDA) receptor antagonist. CGP 37849 is an anticonvulsant in rodents and has antidepressant and anxiolytic-like effects.
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BCC7053
CGP 39551
127910-32-1
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BCC7087
CGP 78608 hydrochloride
CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). Anticonvulsant activity.
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BCC6986
CGS 19755
110347-85-8
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BCC7757
7-Chlorokynurenic acid sodium salt
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery.
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BCC6577
7-Chlorokynurenic acid
7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery.


