Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 44

  1. Cat.No. Product Name Information/Activity
  2. BCC1561 Etifoxine hydrochloride Etifoxine hydrochloride (HOE 36-801 hydrochlorid) is potentiator of GABAA receptor function in cultured neurons. Etifoxine hydrochloride chemical structure
  3. BCC1150 Etomidate Etomidate(R-16659) is a GABAA receptors agonist, which is a short acting intravenous anaesthetic agent used for the induction of general anaesthesia. Etomidate chemical structure
  4. BCC4456 Flupirtine maleate Flupirtine Maleate(D 9998) is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties. Flupirtine maleate chemical structure
  5. BCC7397 Ganaxolone 38398-32-2 Ganaxolone chemical structure
  6. BCC7720 Indiplon 325715-02-4 Indiplon chemical structure
  7. BCC7009 Loreclezole hydrochloride Loreclezole, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors. Loreclezole hydrochloride chemical structure
  8. BCC7984 MaxiPost Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo. MaxiPost chemical structure
  9. BCC6167 Ocinaplon 96604-21-6 Ocinaplon chemical structure
  10. BCC7470 Org 20599 156685-94-8 Org 20599 chemical structure
  11. BCC7452 17-PA 694438-95-4 17-PA chemical structure

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