Sleep Research

Sleep is characterized by altered consciousness, it is split into two distinct stages- rapid eye movement (REM) and non-REM. The circadian clock controls the pattern of sleep and wakefulness. It is regulated by the light levels, temperature, metabolites, neurotransmitters, neuropeptides, and neurohormones, which cause a daily fluctuation in expression levels of many sleep-related genes.

Sleep Research Products Targets

Products for Sleep Research - Page 13

Cat.No. Product Name Information/Activity
BCC7378 Proxyfan oxalate 177708-09-7
BCC7963 A 331440 dihydrochloride Selective H<sub>3</sub> antagonist
BCC1863 Pitolisant hydrochloride Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
BCC7291 Carcinine ditrifluoroacetate 56897-53-1
BCC6781 Clobenpropit dihydrobromide Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR. Clobenpropit dihydrobromide acts as partial agonist at histamine H4 receptors (Ki 13 nM). Clobenpropit dihydrobromide also binds to serotonin 5-HT3 receptors (Ki 7.4 nM) and α2A/α2C adrenoceptors (Ki 17.4/7.8 nM). Clobenpropit dihydrobromide increases apoptosis.
BCC7352 Conessine 546-06-5
BCC7357 GT 2016 152241-24-2
BCC7197 Impentamine dihydrobromide 149629-70-9
BCC6793 Iodophenpropit dihydrobromide Iodophenpropit dihydrobromide is a potent and selective histamine H3 receptor antagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD 0.32 nM).
BCC7842 JNJ 10181457 dihydrochloride 544707-20-2