Androgen Receptor - Endocrinology and Hormones

Cat.No. Product Name Information

BCC7811 PF 998425

BCC1070 AZD3514 AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression. AZD3514

BCC3796 ODM-201 Darolutamide (ODM-201;BAY-1841788) is a potent androgen receptor (AR) antagonist with an IC50 of 26 nM in in vitro assay. ODM-201

BCC4364 Flutamide Flutamide is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.

BCC1911 RU 58841 RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 (PSK-3841) has a dramatic effect on hair regrowth.

BCC6069 TFM-4AS-1

BCC7780 Cl-4AS-1

BCC1296 17 alpha-propionate Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.

BCC6536 EPI-001 EPI-001

BCC7749 CITCO CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO

BCC1168 Andarine Andarine (S-4) is an investigational selective androgen receptor modulator (SARM) and an active partial agonist.

BCC2280 TAK-700 (Orteronel) TAK-700 (Orteronel) is a potent and highly selective human 17,20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3.

BCC3758 Cyproterone Acetate Cyproterone acetate is an androgen receptor (AR) antagonist with IC50 of 7.1 nM, as well as a weak progesterone receptor agonist with weak pro-gestational and glucocorticoid activity.

BCC4481 Epiandrosterone Epiandrosterone is a steroid hormone with weak androgenic activity.

BCC4366 Spironolactone Spironolactone is a potent antagonist of the androgen receptor.

BCN2748 Dimethylcurcumin Dimethylcurcumin (ASC-J9) is an androgen receptor degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion.

BCC1754 MK-0773 MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM. MK-0773

BCC1425 BMS-564929 BMS-564929 is an androgen receptor (AR) agonist, binds to androgen receptor (AR) with a Ki of 2.11±0.16 nM.

BCC6979 TCPOBOP TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. TCPOBOP

BCC3910 TOK-001 Galeterone (TOK-001) is a multifunctional antiandrogen and CYP17 inhibitor (IC50=47 nM) in castration resistant prostate cancer (CRPC). TOK-001

BCC2481 Bicalutamide Bicalutamide is a non-steroidal androgen receptor inhibitor.

BCC1268 MDV3100 (Enzalutamide) Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an autophagy activator.

BCC3724 ARN-509 Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. ARN-509

BCC4482 Estradiol valerate Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy drugs.

Products for Androgen Receptor