Products with Antagonists bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6578 | Piperenone |
| 1. Piperenone is an insect antifeeding substance. 2. Piperenone has anti-platelet-activating factor(PAF) activities, it is a PAF-acether antagonist. | |
| BCN6632 | (-)-Corlumine |
| 1. Corlumine exhibits spasmolytic and GABA antagonist activity. | |
| BCN6706 | Yangambin |
| 1. Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role. 2. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests. 3. Yangambin has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. | |
| BCN6785 | Triptinin B |
| 1. Triptinin A and triptinin B are leukotriene D4 antagonist constituents. | |
| BCN6791 | Cytosporone B |
| Cytosporone B is a naturally occurring agonist for Nur77, it also is a Salmonella pathogenicity island 1 (SPI-1)-inhibitor, it may have potential in drug development against antibiotic-resistant Salmonella. Cytosporone B can elevate blood glucose levels in fasting C57 mice, an effect that is accompanied by induction of multiple genes involved in gluconeogenesis. Cytosporone B can inhibit transforming growth factor-b (TGF-β)-induced contraction of human corneal fibroblasts (HCFs), likely as a result of its attenuation of the up-regulation of α-SMA expression. | |
