Products with Anti-proliferation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3526 | Isocurcumenol |
| Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT). | |
| BCN3547 | 7-O-Prenylscopoletin |
| 1. 7-O-Prenylscopoletin and cedrelopsin show high antiproliferative activities against cancer cell lines. | |
| BCN3607 | (-)-beta-Peltatin-5-O-beta-D-glucopyranoside |
| 1. beta-Peltatin-5-O-beta-D-glucopyranoside provides potent cancer cell growth inhibitory activity (GI50 0.1 to <0.03 ug/mL) against a panel of six human cancer cell lines and one murine cancer cell line. 2. beta-Peltatin-5-O-beta-D-glucopyranoside shows modest antiproliferative activities against the A2780 ovarian cancer cell line, with the IC50 value of 4.9 ± 0.1 uM. | |
| BCN3673 | 7-Hydroxyflavone |
| 7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2. It also has excellent antioxidant, anti-inflammatory, and anti-proliferation properties, it may serve as potential protective agents in the treatment of patients with chronic EV71 infection.7-Hydroxyflavone can protect renal cells from NIC-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway; it also can inhibit LPS-induced inflammation via attenuating the production of NO, PGE2 , TNF-α and IL-6. | |
| BCN3699 | Yukovanol |
| 1. Yukovanol inhibits the proliferation of activated HSC-T6 cells in vitro. | |
