Products with Anti-proliferation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4681 | Tenacissoside I |
| Tenacissosides B, C, I and marsdenoside K inhibit the proliferation of Raji, NB4 and K562 cells in vitro significantly, in a dose and time dependent manner. | |
| BCN4690 | Goniothalamin |
| 1. Goniothalamin enhances rather than inhibits the ATPase activity of a cyanobacterial Hsp90 (HtpG) and a yeast Hsp90, increases both K(m) and k(cat) of the Hsp90s. 2. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings. 3. Goniothalamin has gastroprotective activity which is inhibited after pre-treatment with NEM (N-ethylmaleimide) and NSAID (non-steroidal anti-inflammatory drugs), highlighting the importance of sulfhydryl compounds and prostaglandins on Goniothalamin activity. 4. Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cells, induce apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. | |
| BCN4731 | Osthenone |
| 1. Osthenone shows strong activity against the cancer cell lines, whereas it has weak antiproliferative activity against the normal human cell lines. | |
| BCN4831 | Citropten |
| Citropten and valproic acid show antiproliferative effects against A2058 human melanoma cells. | |
| BCN4869 | Erythrodiol 3-palmitate |
| 1. Erythrodiol 3-palmitate has antitumor activity, it inhibited the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL. | |
