Products with Anti-proliferation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5312 | 3-Hydroxy-11-ursen-28,13-olide |
| 1. 3β-Hydroxy-urs-11-en-28,13β-olide exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line. 2. 3β-Hydroxy-urs-11-en-13β,28-olide shows a potent concentration-independent cytoprotective effect against CCl4-induced injury on human hepatoma cell line relative to silymarin as a reference standard. | |
| BCN5313 | 3-Acetoxy-11-ursen-28,13-olide |
| 1. 3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. 2. 3β-Acetoxy-urs-11-en-28,13β-olide exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line. | |
| BCN5330 | (-)-Catechin gallate(CG) |
| (-)-Catechin gallate is a minor constituent in green tea catechins, it inhibits the activity of COX-1 and COX-2 enzymes. Catechin gallate (IC50=53 microM) shows cytotoxicity against the colorectal adenocarcinoma cell line HCT116, it also exhibits strong anti-proliferative and anti-inflammatory activities on pancreatic ductal adenocarcinoma (PDAC) cells. Catechin 3-gallate is a good inhibitor of maltase, with IC50 values of 62 uM, it inhibits both α-glucosidases and rabbit glycogen phosphorylase (GP) in vitro and in cell culture, would contribute to the protection or improvement of type 2 diabetes. | |
| BCN5354 | Acetate gossypol |
| Acetate gossypol has antifertility action. Acetate gossypol is a potent inhibitor of Bcl-2 and Bcl-xl, it has significant antiproliferative and antiapoptotic effects on multiple myeloma cells in vitro and in vivo, it also has apoptosis-inducing activity in primary cultured leukemia cells. | |
| BCN5386 | Notopterol |
| Notopterol is a kind of furanocoumarin that possesses anti-inflammatory, analgesic, and anticancer activities, it shows significant antiproliferative activity against the HepG-2, MCF-7 and C6 cancer cell lines. | |
