Products with Anti-proliferation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5724 | Uvaol |
| Uvaol has anti-inflammatory, anti-proliferative, and vasorelaxing activities. Uvaol reduces cardiac hypertrophy and left ventricle remodeling induced by angiotensin II in mice by diminishing fibrosis and myocyte area; it inhibits the angiotensin II-induced proliferation in a PPAR-γ-dependent manner, while at high doses they activate pathways of programmed cell death that are dependent on JNK and PPAR-γ. | |
| BCN5726 | Erythrodiol |
| Erythrodiol is the precursor of pentacyclic triterpenic acids, it exerts antiproliferative and proapoptotic activity in colon adenocarcinoma cells. Erythrodiol may have interesting therapeutic potential as new vasodilator drugs, thus protecting the cardiovascular system. | |
| BCN5731 | Gyrophoric acid |
| 1. Gyrophoric acid has anti-proliferative/cytotoxic effect. 2. Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations, they can effectively prevent cytotoxic, apoptotic and cytoskeleton alterative activities of 2.5 J/cm(2) UVB in a dose-dependent manner, suggest that vulpinic and gyrophoric acids can be promising cosmetic ingredients to photo-protect human skin cells. | |
| BCN5781 | Isofuranodiene |
| 1. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells. 2. Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. 3. Isofuranodiene can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents. 4. Isofuranodiene at concentrations of 25 and 12.5 lM alone, or in combination with 50 nM nerve growth factor (NGF) , shows a marked stimulation of neuritogenesis,which appears to be a promising neurotrophic and neuroprotective agent. | |
| BCN5810 | Caudatin |
| 1. Caudatin exerts antiproliferative effects on human hepatocellular carcinoma SMMC7721 cells. 2. Caudatin has anticancer activity, due partly to its inhibition of cell proliferation and induction of apoptosis in cancer cells through caspase activation. 3. Caudatin exhibits significantly inhibitory activity against HBV DNA replication with IC50 values in the range of 2.82-7.48 μM. 4. Caudatin inhibits carcinomic human alveolar basal epithelial cell growth and angiogenesis by targeting GSK3β/β-catenin pathway and suppressing VEGF production. | |
