Products with
Anti-proliferation bioactivity
Cat.No.
|
Product Name
|
BCN4424 |
Pyrogallol
|
Pyrogallol is a polyphenol compound, which has anti-fungal, anti-psoriatic, anti-inflammatory, and antiproliferative effects . Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions; it is both a sensitizer, a carcinogenic, and an irritant in female BALB/c mice. |
BCN4464 |
Viscidulin III
|
Viscidulin III (17.4 microM), wogonin (17.4 microM) and luteolin (18.4 microM) were more effective than baicalein (23.0 microM) which reportedly inhibits the proliferation of some cancer cell lines. |
BCN4547 |
Uncinatone
|
1. Uncinatone exhibits inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages with IC50 values of 12.50 uM.
2. Uncinatone shows inhibitory activity against complement system with 50% inhibitory concentrations (IC(50)) values of 87 uM.
3. Uncinatone demonstrates cytotoxic activities against the HL-60 tumour cell line (IC50 < 20 uM).
4. Uncinatone exhibits moderate cytotoxicity, inhibits cell proliferation, and induces cell-cycle G(2)/M phase arrest. |
BCN4591 |
Casegravol
|
1. Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells. |
BCN4638 |
Isodeoxyelephantopin
|
1. Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation .
2. Isodeoxyelephantopin enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibiting NF-kappaB activation and NF-kappaB-regulated gene expression. |