Products with Anti-proliferation bioactivity

Cat.No. Product Name
BCN3709 4,4'-Di-O-methylellagic acid
1. 4,4'-di-O-methylellagic acid is the most effective compound in the inhibition of colon cancer cell proliferation.
BCN3717 Pseudolaric acid A
Pseudolaric acid A and -B can inhibit the growth of particular cell type.
BCN3725 Beta-Tocotrienol
1. Beta-Tocotrienol to serve as a new anticancer agent for treating human lung and brain cancers. 2. Beta-Tocotrienol inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations.
BCN3790 Isokaempferide
1. Isokaempferide shows anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. 2. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea. 3. The hydroxyflavones (luteolin, apigenin and isokaempferide) exert comparable antiproliferative activities against malignant and normal cells. 4. Isokaempferide shows strong inhibitory effect on TNF-alpha-induced liver cell death with the IC50 value of 22.8 microM, suggests that it has hepatoprotective activity.
BCN3816 Gardenin B
Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species. Gardenin B can strongly inhibit biochemical production of nitric oxide (IC50=10.59±0.4 ug/mL).

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