Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 4321 - 4328 of 9359 hot products
| Catalog No. | Product Name |
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| BCN2208 | Ergocalciferol |
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Ergocalciferol (Vitamin D2) is a selective inhibitor of mammalian DNA polymerase A (pol A) with IC50 of 123 mM. Ergocalciferol can delay the development of secondary hyperparathyroidism in children with CKD2-3. Ergocalciferol can cause HL-60 apoptosis via a modulation of mitochondria involving ROS production, GSH depletion, caspase activation, and Fas induction, on the basis of anticancer activity of ergocalciferol, it may be feasible to develop chemopreventive agents from edible mushrooms or hop. Ergocalciferol can prevent glucocorticoid-induced bone loss, but even increase lumbar spine and femoral neck bone mineral densities (BMD) in postmenopausal women commencing glucocorticoid therapy, it also
is safe and effective in reducing the risk of a fracture in elderly patients with AD. |
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| BCN2209 | Vitamin K1 |
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Vitamin K1, a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. Vitamin K1 has anticoagulation activity, it may attenuate liver fibrosis by inhibiting hepatic stellate cell activation in bile duct-ligated rats; it inhibits diabetic-cataract by modulating lens Ca2+ homeostasis and its hypoglycemic effect through its direct action on the pancreas.Vitamin K1 may substantially contribute to reducing postmenopausal bone loss at the site of the femoral neck.
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| BCN2210 | (S)-(+)-Abscisic acid |
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Abscisic acid (ABA) is a ubiquitous hormone that regulates plant growth, development and responses to environmental stresses, plays a crucial role in the plant's response to both biotic and abiotic stress. Treatment with low concentrations of abscisic acid ( 10 to 100 microM) induced an antioxidative defence response against oxidative damage, but a high concentration of ABA (1,000 microM) induced an excessive generation of AOS and led to an oxidative damage in plant cells.
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| BCN2211 | 11Beta-hydroxyprogesterone |
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The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.
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| BCN2212 | 3-Hydroxybutyric acid |
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3-Hydroxybutyric acid is a ketone body and acts as an indicator of energy balance and a central regulator of energy homeostasis. 3-Hydroxybutyric acid has anesthetic actions, which are due to the metabolite's abilities to alter physical properties of cell membranes, leading to indirect effects on membrane protein function.
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| BCN2213 | 3-Nitro-L-tyrosine |
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3-Nitro-L-tyrosine,an oxidative stress marker associated with neurodegenerative disorders.3-Nitro-L-tyrosine could as solid-phase extraction (SPE) sorbent material.
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| BCN2214 | Dipalmitin |
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Dipalmitin has templating effects on soft palm mid fraction crystals.
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| BCN2215 | Arachidonic acid |
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Arachidonic acid is 1 of only 2 unsaturated fatty acids retained in the ovaries of crustaceans and an inhibitor of HR97g, a nuclear receptor expressed in adult ovaries. Arachidonic acid induces retinal arteriolar vasodilation by inhibiting subcellular Ca(2+)-signaling activity in retinal arteriolar myocytes, most likely through a mechanism involving the inhibition of L-type Ca(2+)-channel activity. Arachidonic acid causes an increase in free cytoplasmic calcium concentration ([Ca2+]i) in differentiated skeletal multinucleated myotubes C2C12 and does not induce calcium response in C2C12 myoblasts.
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