Coumarins - Natural Products

Cat.No. Product Name Information

BCN7569 Demethylluvangetin Botanical source: The roots of Toddalia asiatica(CAS NO.:64652-10-4)

BCN2663 Demethylwedelolactone Demethylwedelolactone is a naturally occurring coumestan isolated from Eclipta alba. Demethylwedelolactone is a potent trypsin inhibitor with an IC50 of 3.0 μM. Demethylwedelolactone suppresses cell motility and cell invasion of breast cancer cell.(CAS NO.:6468-55-9)

BCN4192 Heraclenol acetonide Botanical source: The herbs of Heracleum repula Franch.(CAS NO.:64790-68-7)

BCN4198 Phebalosin Botanical source: The herbs of Murraya exotica L.(CAS NO.:6545-99-9)

BCN7689 Peucedanol 7-O-glucoside Botanical source: The roots of Peucedanum praeruptorum Dunn.(CAS NO.:65853-04-5)

BCN7688 Peucedanol 3'-O-glucoside Botanical source: The roots of Peucedanum praeruptorum Dunn.(CAS NO.:65891-61-4)

BCN4219 Psoralen Psoralen (Furocoumarin) is an active ingredient from Fructus Psoraleae; has anticancer activity.(CAS NO.:66-97-7)

BCN7681 Glycyrin Botanical source: The roots of Glycyrrhiza uralensis.(CAS NO.:66056-18-6)

BCC3917 8'-Epicleomiscosin A Botanical source: The herbs of Buxus sinica(CAS NO.:)

BCN4242 6',7'-Dihydroxybergamottin acetonide Botanical source: The peels of Citrus maxima(CAS NO.:684217-08-1)

BCN3704 Qianhucoumarin G Botanical source: The roots of Peucedanum praeruptorum(CAS NO.:68692-61-5)

BCN1377 Osthol hydrate Osthol hydrate is a natural product isolated from F. schottiana.(CAS NO.:69219-24-5)

BCN4599 Pd-C-II Botanical source: The herbs of Peucedanum decursivum Maxim.(CAS NO.:) Pd-C-II

BCN4991 Praeruptorin C Praeruptorin C is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.7.(CAS NO.:72463-77-5)

BCN3637 O-Methylcedrelopsin Botanical source: The roots of Toddalia asiatica Lam.(CAS NO.:72916-61-1)

BCN4987 Praeruptorin A (±)-Praeruptorin A is the di-esterified product of cis-khellactone (CKL) and the major active ingredient in Peucedani Radix which consists of the dried roots of Peucedanum praeruptorumDunn (Apiaceae). (±)-Praeruptorin A has been widely employed as one of the famous traditional Chinese medicines (TCMs) for the treatment of cough with thick sputum and dyspnea, nonproductive cough and upper respiratory infections for centuries in China. (±)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker.(CAS NO.:73069-25-7)

BCN4989 (+)-Praeruptorin A Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation.(CAS NO.:73069-27-9)

BCN4990 Praeruptorin D Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs).(CAS NO.:73069-28-0)

BCN2494 Oxypeucedanin Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation. Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration.(CAS NO.:737-52-0)

BCN2733 Bergamotine Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.(CAS NO.:7380-40-7)

BCN4296 8-Geranyloxypsoralen 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM.(CAS NO.:7437-55-0)

BCN4591 Casegravol Botanical source: The herbs of Murraya paniculata(CAS NO.:74474-76-3)

BCN1362 Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside] Botanical source: The roots of Heracleum stenopterum(CAS NO.:765316-44-7)

BCN4320 Cleomiscosin A Botanical source: The herbs of Buxus sinica(CAS NO.:76948-72-6)

BCN3898 Cleomiscosin B Botanical source: The herbs of Paederia scandens (Lour.) Merr(CAS NO.:76985-93-8)

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