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16 alpha-Hydroxytrametenolic acid

CAS# 176390-68-4

16 alpha-Hydroxytrametenolic acid

Catalog No. BCN2917----Order now to get a substantial discount!

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16 alpha-Hydroxytrametenolic acid: 5mg $322 In Stock
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Quality Control of 16 alpha-Hydroxytrametenolic acid

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Chemical structure

16 alpha-Hydroxytrametenolic acid

3D structure

Chemical Properties of 16 alpha-Hydroxytrametenolic acid

Cas No. 176390-68-4 SDF Download SDF
PubChem ID 132285301 Appearance Powder
Formula C30H48O4 M.Wt 472.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R)-2-[(3S,10S,13R,14R,16R,17R)-3,16-dihydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-enoic acid
SMILES CC(=CCCC(C1C(CC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C)O)C(=O)O)C
Standard InChIKey LPHOGVFYEBRXSC-LUXVNGTFSA-N
Standard InChI InChI=1S/C30H48O4/c1-18(2)9-8-10-19(26(33)34)25-22(31)17-30(7)21-11-12-23-27(3,4)24(32)14-15-28(23,5)20(21)13-16-29(25,30)6/h9,19,22-25,31-32H,8,10-17H2,1-7H3,(H,33,34)/t19-,22-,23?,24+,25+,28-,29-,30+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 16 alpha-Hydroxytrametenolic acid

The sclerotium of Poria cocos(Schw.)Wolf

Biological Activity of 16 alpha-Hydroxytrametenolic acid

Description16 alpha-Hydroxytrametenolic acid can inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema.

Protocol of 16 alpha-Hydroxytrametenolic acid

Structure Identification
Chem Pharm Bull (Tokyo). 1996 Apr;44(4):847-9.

Isolation of inhibitors of TPA-induced mouse ear edema from Hoelen, Poria cocos.[Pubmed: 8681415]


METHODS AND RESULTS:
Triterpene carboxylic acids were isolated from the methanol extract of Hoelen, Poria cocos, and found to inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema.
CONCLUSIONS:
Their chemical structures were identified as 3 beta,-16 alpha-dihydroxylanosta-7,9(11),24-trien-21-oic acid, 16 alpha-hydroxydehydropachymic acid, 16 alpha-Hydroxytrametenolic acid and dehydrotumulosic acid.

16 alpha-Hydroxytrametenolic acid Dilution Calculator

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Preparing Stock Solutions of 16 alpha-Hydroxytrametenolic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1155 mL 10.5775 mL 21.1551 mL 42.3101 mL 52.8877 mL
5 mM 0.4231 mL 2.1155 mL 4.231 mL 8.462 mL 10.5775 mL
10 mM 0.2116 mL 1.0578 mL 2.1155 mL 4.231 mL 5.2888 mL
50 mM 0.0423 mL 0.2116 mL 0.4231 mL 0.8462 mL 1.0578 mL
100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4231 mL 0.5289 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 16 alpha-Hydroxytrametenolic acid

Isolation of inhibitors of TPA-induced mouse ear edema from Hoelen, Poria cocos.[Pubmed:8681415]

Chem Pharm Bull (Tokyo). 1996 Apr;44(4):847-9.

Triterpene carboxylic acids were isolated from the methanol extract of Hoelen, Poria cocos, and found to inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema. Their chemical structures were identified as 3 beta,-16 alpha-dihydroxylanosta-7,9(11),24-trien-21-oic acid, 16 alpha-hydroxydehydropachymic acid, 16 alpha-Hydroxytrametenolic acid and dehydrotumulosic acid.

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