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24(28)-Dehydroergosterol

CAS# 29560-24-5

24(28)-Dehydroergosterol

Catalog No. BCX1146----Order now to get a substantial discount!

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Quality Control of 24(28)-Dehydroergosterol

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Chemical structure

24(28)-Dehydroergosterol

3D structure

Chemical Properties of 24(28)-Dehydroergosterol

Cas No. 29560-24-5 SDF Download SDF
PubChem ID 11090531.0 Appearance Powder
Formula C28H42O M.Wt 394.64
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3S,9S,10R,13R,14R,17R)-10,13-dimethyl-17-[(E,2R)-6-methyl-5-methylidenehept-3-en-2-yl]-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
SMILES CC(C)C(=C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C
Standard InChIKey SQFQJKZSFOZDJY-CVGLIYDESA-N
Standard InChI InChI=1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18,20,22,24-26,29H,3,11-17H2,1-2,4-6H3/b8-7+/t20-,22+,24-,25+,26+,27+,28-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

24(28)-Dehydroergosterol Dilution Calculator

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24(28)-Dehydroergosterol Molarity Calculator

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Preparing Stock Solutions of 24(28)-Dehydroergosterol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.534 mL 12.6698 mL 25.3395 mL 50.6791 mL 63.3489 mL
5 mM 0.5068 mL 2.534 mL 5.0679 mL 10.1358 mL 12.6698 mL
10 mM 0.2534 mL 1.267 mL 2.534 mL 5.0679 mL 6.3349 mL
50 mM 0.0507 mL 0.2534 mL 0.5068 mL 1.0136 mL 1.267 mL
100 mM 0.0253 mL 0.1267 mL 0.2534 mL 0.5068 mL 0.6335 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 24(28)-Dehydroergosterol

Neutral lipids in the cells and cell envelope fractions of aerobic baker's yeast and anaerobic brewer's yeast.[Pubmed:1091369]

Chem Phys Lipids. 1975 Feb;14(1):15-32.

The neutral lipids from whole cells and cell envelopes of aerobic Saccharomyces cerevisiae and anaerobic Sacch. carlsbergensis and the cell walls isolated from the cell envelopes were analysed. The effect of anaerobiosis was particularly clear on the neutral lipid composition of the plasma membrane. Compared to the anaerobic membrane, the aerobic membrane contained more C16:1, C18:1 and other unsaturated fatty acids, more total sterol, more than ten times as much ergosterol and less than one tenth as much squalene, reflecting differences between the aerobic and anaerobic whole cellmthe main sterol in the aerobic membrane ergosterol, was mainly in the free form, whereas zymosterol, 24(28)-Dehydroergosterol, epi- or fecosterol and lanosterol were predominantly esterified. In contrast, the anerobic membrane contained small amounts of biosynthetic sterol precursors of ergosterol (mainly esterified), and was clearly richer in saturated fatty acids having a greater variation in chain length and in 18:2 acid. Both plasma membranes contained a considerable amount of triacyglycerols, while the amount of lower acylglycerols was clearly higher in the anaerobic plasma membrane. The lipid composition of both cell walls were relatively similar, consisting mainly of triacylglycerols and lower acylglycerols.

Nystatin-resistant mutants of yeast: alterations in sterol content.[Pubmed:5122815]

J Bacteriol. 1971 Oct;108(1):69-73.

Mutants of the genes nys1 and nys3 differ from sensitive strains (nys(+)) in their sterol content. Ultraviolet absorption spectra of the nonsaponifiable material extracted from cells of nys(+) demonstrated the presence of ergosterol and 24(28)-Dehydroergosterol. In nys1 mutants, the spectrum suggests the presence of a new sterol. The absorption spectrum of extracts from nys3 mutants indicates absence of both ergosterol and 24(28)-Dehydroergosterol and presence of another new sterol. Conversion of nys(+) and nys3 to petite results in loss of 24(28)-Dehydroergosterol in the former and the new sterol in the latter, whereas the new sterol in nys1 is only reduced. The sterols in ethanol-grown cells of all genotypes are essentially the same as is found for growth on glucose. With the exception of nys3 grown on ethanol, the mutants do not appear to be at a disadvantage compared to wild type.

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