3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olideCAS# 828935-47-3 |
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Cas No. | 828935-47-3 | SDF | Download SDF |
PubChem ID | 70698071 | Appearance | Powder |
Formula | C26H38O3 | M.Wt | 398.6 |
Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | (4S)-4-[(5R,9R,10R,13S,14S,17S)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxolan-2-one | ||
SMILES | CC1(C2CC=C3C(C2(CCC1=O)C)CCC4(C3(CCC4C5CC(=O)OC5)C)C)C | ||
Standard InChIKey | BWKLKUMHNBYPDA-APSMHXCZSA-N | ||
Standard InChI | InChI=1S/C26H38O3/c1-23(2)20-7-6-19-18(24(20,3)11-10-21(23)27)9-13-25(4)17(8-12-26(19,25)5)16-14-22(28)29-15-16/h6,16-18,20H,7-15H2,1-5H3/t16-,17+,18+,20+,24-,25+,26-/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. 3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone shows significant inhibitory activities against human cancer cell lines in vitro. |
3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide Dilution Calculator
3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.5088 mL | 12.5439 mL | 25.0878 mL | 50.1756 mL | 62.7195 mL |
5 mM | 0.5018 mL | 2.5088 mL | 5.0176 mL | 10.0351 mL | 12.5439 mL |
10 mM | 0.2509 mL | 1.2544 mL | 2.5088 mL | 5.0176 mL | 6.272 mL |
50 mM | 0.0502 mL | 0.2509 mL | 0.5018 mL | 1.0035 mL | 1.2544 mL |
100 mM | 0.0251 mL | 0.1254 mL | 0.2509 mL | 0.5018 mL | 0.6272 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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Chemical constituents from Dysoxylum lenticellatum
Chinese Traditional & Herbal Drugs, 2012, 43(1):38-42.
To study the chemical constituents from the stems of Dysoxylum lenticellatum and their cytotoxic activities. Methods Silica gel, RP-18, and Sephadex LH-20 column chromatography techniques were used for separation and purification of the compounds and extensive spectral analysis spectra were employed for structural elucidation. The cytotoxic activity was evaluated by MTT method. Results Twelve compounds were isolated from D. lenticellatum and their structures were identified as β-sitosterol (1), stigmasterol (2), 3-oxo-24, 25, 26, 27-tetranortirucall-7-en-23,21-lactone (3), 3α-hydroxy-24, 25, 26, 27-tetranortirucall-7-ene-23(21)-lactone (4), laxiracemosin H (5), laxiracemosin B (6), 24, 25-epoxy-tirucall-7-ene-3, 23-dione (7), butyrospermol (8), oleanolic acid (9), taraxerone (10), taraxerol (11), and 8-hydroxy-6-methoxy-3-pentylisocoumarin (12). Conclusion All of these compounds are isolated from D. lenticellatum for the first time and the compounds 8, 10—12 are reported from the plants in Dysoxylum Bl. for the first time. What’s more, compounds 5 and 6 are tirucallane-type alkaloids and compound 3 shows significant inhibitory activities against human cancer cell lines in vitro.