7,4'-Dihydroxy-8-methylflavanCAS# 82925-55-1 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 82925-55-1 | SDF | Download SDF |
| PubChem ID | 442361 | Appearance | Powder |
| Formula | C16H16O3 | M.Wt | 256.30 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S)-2-(4-hydroxyphenyl)-8-methyl-3,4-dihydro-2H-chromen-7-ol | ||
| SMILES | CC1=C(C=CC2=C1OC(CC2)C3=CC=C(C=C3)O)O | ||
| Standard InChIKey | GDHZZZRERDPSTA-HNNXBMFYSA-N | ||
| Standard InChI | InChI=1S/C16H16O3/c1-10-14(18)8-4-12-5-9-15(19-16(10)12)11-2-6-13(17)7-3-11/h2-4,6-8,15,17-18H,5,9H2,1H3/t15-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. 7,4'-Dihydroxy-8-methylflavan can significantly promote mesenchymal stem cells (MSCs) osteogenic differentiation by increasing the levels of alkaline phosphatase (ALP) activity. 2. 7,4'-Dihydroxy-8-methylflavan has free radical scavenging properties. |
7,4'-Dihydroxy-8-methylflavan Dilution Calculator
7,4'-Dihydroxy-8-methylflavan Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.9017 mL | 19.5084 mL | 39.0168 mL | 78.0336 mL | 97.5419 mL |
| 5 mM | 0.7803 mL | 3.9017 mL | 7.8034 mL | 15.6067 mL | 19.5084 mL |
| 10 mM | 0.3902 mL | 1.9508 mL | 3.9017 mL | 7.8034 mL | 9.7542 mL |
| 50 mM | 0.078 mL | 0.3902 mL | 0.7803 mL | 1.5607 mL | 1.9508 mL |
| 100 mM | 0.039 mL | 0.1951 mL | 0.3902 mL | 0.7803 mL | 0.9754 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Fmoc-Osu
Catalog No.:BCC2804
CAS No.:82911-69-1
- 3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide
Catalog No.:BCN1338
CAS No.:828935-47-3
- (R)-(+)-Etomoxir sodium salt
Catalog No.:BCC7946
CAS No.:828934-41-4
- 2,3-Dihydroisoginkgetin
Catalog No.:BCN4035
CAS No.:828923-27-9
- Cyclo(Tyr-Leu)
Catalog No.:BCN2432
CAS No.:82863-65-8
- Echinacoside
Catalog No.:BCN4953
CAS No.:82854-37-3
- Pingpeimine B
Catalog No.:BCN8408
CAS No.:82851-52-3
- Pingpeimine A
Catalog No.:BCN8407
CAS No.:82841-67-6
- Perindopril
Catalog No.:BCC4223
CAS No.:82834-16-0
- cGMP Dependent Kinase Inhibitor Peptide
Catalog No.:BCC8084
CAS No.:82801-73-8
- H-D-HoPhe-OH
Catalog No.:BCC3239
CAS No.:82795-51-5
- Nefazodone hydrochloride
Catalog No.:BCC7479
CAS No.:82752-99-6
- CI 898 trihydrochloride
Catalog No.:BCC7248
CAS No.:82952-64-5
- Nafamostat Mesylate(FUT-175)
Catalog No.:BCC1228
CAS No.:82956-11-4
- 11-O-Galloylbergenin
Catalog No.:BCN6637
CAS No.:82958-44-9
- 4-O-Galloylbergenin
Catalog No.:BCN6643
CAS No.:82958-45-0
- Tolrestat
Catalog No.:BCC4084
CAS No.:82964-04-3
- 4-Aminoantipyrine
Catalog No.:BCC8683
CAS No.:83-07-8
- Phenindione
Catalog No.:BCC4699
CAS No.:83-12-5
- 1-Indanone
Catalog No.:BCN2245
CAS No.:83-33-0
- Methylprednisolone
Catalog No.:BCC2256
CAS No.:83-43-2
- Deoxycholic acid
Catalog No.:BCN1288
CAS No.:83-44-3
- Beta-Sitosterol
Catalog No.:BCN1015
CAS No.:83-46-5
- Stigmasterol
Catalog No.:BCN4376
CAS No.:83-48-7
Three new flavanoids from artificially induced dragon's blood of Dracaena cambodiana.[Pubmed:28597686]
J Asian Nat Prod Res. 2018 Jan;20(1):55-61.
Three new flavanoids, (2R)-7,4'-dihydroxy-8-methylflavan (1), (2R)-7,4'-dihydroxy-6-methylflavan (2), and (3R)-7,3',4'-trihydroxyhomoisoflavan (3), together with seven known compounds (4-10), were isolated from artificially induced dragon's blood of Dracaena cambodiana, and their structures were determined based on HR-ESI-MS and extensive spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 2 exhibited weak cytotoxicity against BEL-7402 cells line with the IC50 value of 39.2 muM. In addition, compound 3 showed significant acetylcholinesterase (AChE) inhibitory activity.
Isolation and chatacterization of homoisoflavonoids from Dracaena cochinchinensis and their osteogenic activities in mouse mesenchymal stem cells.[Pubmed:27497307]
J Pharm Biomed Anal. 2016 Sep 10;129:466-472.
Two new homoisoflavonoids, dracaeconolide A (1) and dracaeconolide B (2), together with ten known compounds, namely (3R)-7,4'-dihydroxy-8-methoxyhomoisoflavane (3), (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane (4), (3R)-7,4'-dihydroxy-5-methoxy-homoisoflavane (5), (3R)-6,4'-dihydroxy-8-methoxyhomoisoflavan (6), 7,4'-dihydroxy-8-methylflavan (7), (2R)-7,4'-dihydroxy-5-methoxy-8-methylflavan (8), 5,4'-dihydroxy-7-methoxy-6-methylflavane (9), 7,4'-dihydroxy-3'-methoxyflavan (10), 7,4'-dihydroxyflavan (11), 4,4'-dihydroxy-2,6-dimethoxydihydrochlcone (12), were isolated from the red resin of Dracaena cochinchinensis (dragon's blood, DB). All the compounds were then evaluated for their effects on mouse bone marrow-derived mesenchymal stem cells (MSCs) proliferation using CCK8 assay and their abilities in promoting MSCs differentiating into osteoblast through the assay of alkaline phosphatase (ALP) activity in vitro. Compounds 2, 3, 4, 7, 9, and 11, at a concentration of 10muM with no cytotoxicity, significantly promoted MSC osteogenic differentiation by increasing the levels of ALP activity to percents of 159.6+/-5.9, 167.6+/-10.9, 162.0+/-1.4, 151.3+/-4.0, 171.0+/-8.2, and 169.9+/-7.3 in relative to the control, respectively. The results of ALP staining were in accordance to that of ALP activity.
A methylflavan with free radical scavenging properties from Pancratium littorale.[Pubmed:11163938]
Fitoterapia. 2001 Jan;72(1):35-9.
The isolation of 7,4'-dihydroxy-8-methylflavan (1) from the dichloromethane extract of Pancratium littorale stem was guided by an assay for free radical scavenging activity towards the 2,2-diphenyl-1-picryl-hydrazyl radical (DPPH). The structure of 1 was established by spectrometric methods including UV, EI mass spectrometry, 1H and 13C-NMR. The free radical scavenging properties of 1 were quantified in solution using spectrophotometry.
