Amaronol A

CAS# 226560-96-9

Amaronol A

2D Structure

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Quality Control of Amaronol A

3D structure

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Amaronol A

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Chemical Properties of Amaronol A

Cas No. 226560-96-9 SDF Download SDF
PubChem ID 485521 Appearance Powder
Formula C15H12O8 M.Wt 320.3
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2,4,6-trihydroxy-2-[(3,4,5-trihydroxyphenyl)methyl]-1-benzofuran-3-one
SMILES C1=C(C=C(C(=C1O)O)O)CC2(C(=O)C3=C(C=C(C=C3O2)O)O)O
Standard InChIKey KZFYMOSMINTUQG-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Amaronol A

The barks of Pseudolarix kaempferi

Biological Activity of Amaronol A

DescriptionStandard reference
In vitro

Two auronols from Pseudolarix amabilis.[Pubmed: 10346966]

J Nat Prod. 1999 May;62(5):767-9.


METHODS AND RESULTS:
Two new auronols, Amaronol A (1) and amaronol B (2), were isolated from the bark of Pseudolarix amabilis, along with pseudolaric acid B (3), pseudolaric acid C (4), demethoxydeacetoxy-pseudolaric acid B (5), pseudolaric acid B-beta-D-glucoside (6), pseudolaric acid A-beta-D-glucoside (7), and myricetin (8). The structures of Amaronol A and amaronol B were established by spectral data interpretation as 2,4,6-trihydroxy-2-[(3',4',5'-trihydroxyphenyl) methyl]-3(2H)-benzofuranone and 2,4,6-trihydroxy-2-[(3', 5'-dihydroxy-4'-methoxyphenyl) methyl]-3(2H)-benzofuranone, respectively.
CONCLUSIONS:
Antimicrobial testing results of the eight compounds indicated that only pseudolaric acid B was active against Candida albicans (MIC, 3.125 microg/mL; MFC, 6.25 microg/mL), while myricetin was marginally active against Trichophyton mentagrophytes (MIC, 50 microg/mL).

Amaronol A Dilution Calculator

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Amaronol A Molarity Calculator

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Preparing Stock Solutions of Amaronol A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1221 mL 15.6104 mL 31.2207 mL 62.4415 mL 78.0518 mL
5 mM 0.6244 mL 3.1221 mL 6.2441 mL 12.4883 mL 15.6104 mL
10 mM 0.3122 mL 1.561 mL 3.1221 mL 6.2441 mL 7.8052 mL
50 mM 0.0624 mL 0.3122 mL 0.6244 mL 1.2488 mL 1.561 mL
100 mM 0.0312 mL 0.1561 mL 0.3122 mL 0.6244 mL 0.7805 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Amaronol A

Two auronols from Pseudolarix amabilis.[Pubmed:10346966]

J Nat Prod. 1999 May;62(5):767-9.

Two new auronols, amaronols A (1) and B (2), were isolated from the bark of Pseudolarix amabilis, along with pseudolaric acid B (3), pseudolaric acid C (4), demethoxydeacetoxy-pseudolaric acid B (5), pseudolaric acid B-beta-D-glucoside (6), pseudolaric acid A-beta-D-glucoside (7), and myricetin (8). The structures of amaronols A and B were established by spectral data interpretation as 2,4,6-trihydroxy-2-[(3',4',5'-trihydroxyphenyl) methyl]-3(2H)-benzofuranone and 2,4,6-trihydroxy-2-[(3', 5'-dihydroxy-4'-methoxyphenyl) methyl]-3(2H)-benzofuranone, respectively. Antimicrobial testing results of the eight compounds indicated that only pseudolaric acid B was active against Candida albicans (MIC, 3.125 microg/mL; MFC, 6.25 microg/mL), while myricetin was marginally active against Trichophyton mentagrophytes (MIC, 50 microg/mL).

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