Amaronol B

CAS# 226561-02-0

Amaronol B

2D Structure

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Quality Control of Amaronol B

3D structure

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Amaronol B

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Chemical Properties of Amaronol B

Cas No. 226561-02-0 SDF Download SDF
PubChem ID 485522 Appearance Powder
Formula C16H14O8 M.Wt 334.3
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-[(3,5-dihydroxy-4-methoxyphenyl)methyl]-2,4,6-trihydroxy-1-benzofuran-3-one
SMILES COC1=C(C=C(C=C1O)CC2(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
Standard InChIKey YCDTYNVODFTPCZ-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Amaronol B

The barks of Pseudolarix kaempferi

Biological Activity of Amaronol B

In vitro

Two auronols from Pseudolarix amabilis.[Pubmed: 10346966]

J Nat Prod. 1999 May;62(5):767-9.


METHODS AND RESULTS:
Two new auronols, amaronol A (1) and Amaronol B (2), were isolated from the bark of Pseudolarix amabilis, along with pseudolaric acid B (3), pseudolaric acid C (4), demethoxydeacetoxy-pseudolaric acid B (5), pseudolaric acid B-beta-D-glucoside (6), pseudolaric acid A-beta-D-glucoside (7), and myricetin (8). The structures of amaronol A and Amaronol B were established by spectral data interpretation as 2,4,6-trihydroxy-2-[(3',4',5'-trihydroxyphenyl) methyl]-3(2H)-benzofuranone and 2,4,6-trihydroxy-2-[(3', 5'-dihydroxy-4'-methoxyphenyl) methyl]-3(2H)-benzofuranone, respectively.
CONCLUSIONS:
Antimicrobial testing results of the eight compounds indicated that only pseudolaric acid B was active against Candida albicans (MIC, 3.125 microg/mL; MFC, 6.25 microg/mL), while myricetin was marginally active against Trichophyton mentagrophytes (MIC, 50 microg/mL).

Amaronol B Dilution Calculator

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Amaronol B Molarity Calculator

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Preparing Stock Solutions of Amaronol B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9913 mL 14.9566 mL 29.9133 mL 59.8265 mL 74.7831 mL
5 mM 0.5983 mL 2.9913 mL 5.9827 mL 11.9653 mL 14.9566 mL
10 mM 0.2991 mL 1.4957 mL 2.9913 mL 5.9827 mL 7.4783 mL
50 mM 0.0598 mL 0.2991 mL 0.5983 mL 1.1965 mL 1.4957 mL
100 mM 0.0299 mL 0.1496 mL 0.2991 mL 0.5983 mL 0.7478 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Amaronol B

Two auronols from Pseudolarix amabilis.[Pubmed:10346966]

J Nat Prod. 1999 May;62(5):767-9.

Two new auronols, amaronols A (1) and B (2), were isolated from the bark of Pseudolarix amabilis, along with pseudolaric acid B (3), pseudolaric acid C (4), demethoxydeacetoxy-pseudolaric acid B (5), pseudolaric acid B-beta-D-glucoside (6), pseudolaric acid A-beta-D-glucoside (7), and myricetin (8). The structures of amaronols A and B were established by spectral data interpretation as 2,4,6-trihydroxy-2-[(3',4',5'-trihydroxyphenyl) methyl]-3(2H)-benzofuranone and 2,4,6-trihydroxy-2-[(3', 5'-dihydroxy-4'-methoxyphenyl) methyl]-3(2H)-benzofuranone, respectively. Antimicrobial testing results of the eight compounds indicated that only pseudolaric acid B was active against Candida albicans (MIC, 3.125 microg/mL; MFC, 6.25 microg/mL), while myricetin was marginally active against Trichophyton mentagrophytes (MIC, 50 microg/mL).

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