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Boric acid

CAS# 10043-35-3

Boric acid

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Chemical structure

Boric acid

3D structure

Chemical Properties of Boric acid

Cas No. 10043-35-3 SDF Download SDF
PubChem ID 7628 Appearance Powder
Formula H3BO3 M.Wt 61.83
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble to 600 mM in water
Chemical Name boric acid
SMILES B(O)(O)O
Standard InChIKey KGBXLFKZBHKPEV-UHFFFAOYSA-N
Standard InChI InChI=1S/BH3O3/c2-1(3)4/h2-4H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Boric acid

DescriptionWidely used in buffers for electrophoresis.

Boric acid Dilution Calculator

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Boric acid Molarity Calculator

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Preparing Stock Solutions of Boric acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 16.1734 mL 80.8669 mL 161.7338 mL 323.4676 mL 404.3345 mL
5 mM 3.2347 mL 16.1734 mL 32.3468 mL 64.6935 mL 80.8669 mL
10 mM 1.6173 mL 8.0867 mL 16.1734 mL 32.3468 mL 40.4334 mL
50 mM 0.3235 mL 1.6173 mL 3.2347 mL 6.4694 mL 8.0867 mL
100 mM 0.1617 mL 0.8087 mL 1.6173 mL 3.2347 mL 4.0433 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Boric acid

Polar Localization of the NIP5;1 Boric Acid Channel Is Maintained by Endocytosis and Facilitates Boron Transport in Arabidopsis Roots.[Pubmed:28341806]

Plant Cell. 2017 Apr;29(4):824-842.

Boron uptake in Arabidopsis thaliana is mediated by nodulin 26-like intrinsic protein 5;1 (NIP5;1), a Boric acid channel that is located preferentially on the soil side of the plasma membrane in root cells. However, the mechanism underlying this polar localization is poorly understood. Here, we show that the polar localization of NIP5;1 in epidermal and endodermal root cells is mediated by the phosphorylation of Thr residues in the conserved TPG (ThrProGly) repeat in the N-terminal region of NIP5;1. Although substitutions of Ala for three Thr residues in the TPG repeat did not affect lateral diffusion in the plasma membrane, these substitutions inhibited endocytosis and strongly compromised the polar localization of GFP-NIP5;1. Consistent with this, the polar localization was compromised in micro subunit mutants of the clathrin adaptor AP2. The Thr-to-Ala substitutions did not affect the boron transport activity of GFP-NIP5;1 in Xenopus laevis oocytes but did inhibit the ability to complement boron translocation to shoots and rescue growth defects in nip5;1-1 mutant plants under boron-limited conditions. These results demonstrate that the polar localization of NIP5;1 is maintained by clathrin-mediated endocytosis, is dependent on phosphorylation in the TPG repeat, and is necessary for the efficient transport of boron in roots.

Boric acid-destabilized lithium borohydride with a 5.6 wt% dehydrogenation capacity at moderate temperatures.[Pubmed:28300266]

Dalton Trans. 2017 Apr 5;46(14):4499-4503.

Boric acid effectively promotes the dehydrogenation of lithium borohydride due to the interactions between protonic and hydridic hydrogen. The simple mixture of LiBH4-(4/3)B(OH)3 can release 5.6 wt% hydrogen below 180 degrees C with only a trace amount of water, thus constituting a highly attractive single-use hydrogen storage material.

Ecotoxicity of boric acid in standard laboratory tests with plants and soil organisms.[Pubmed:28314961]

Ecotoxicology. 2017 May;26(4):471-481.

To verify the continuous sensitivity of ecotoxicological tests (mainly the test organisms), reference substances with known toxicity are regularly tested. Ideally, this substance(s) would lack specificity in its mode action, be bioavailable and readily attainable with cost-effective means of chemical characterization. Boric acid has satisfied these criteria, but has most recently been characterized as a substance of very high concern, due to reproductive effects in humans, thus limiting its recommendation as an ideal reference toxicant. However, there is probably no other chemical for which ecotoxicity in soil has been so intensively studied; an extensive literature review yielded lethal (including avoidance) and sublethal data for 38 taxa. The ecotoxicity data were evaluated using species sensitivity distributions, collectively across all taxa, and separately according to species type, endpoints, soil type and duration. The lack of specificity in the mode of action yielded broad toxicity among soil taxa and soil types, and provided a collective approach to assessing species sensitivity, while taking into consideration differences in test methodologies and exposure durations. Toxicity was species-specific with Folsomia candida and enchytraied species demonstrating the most sensitivity; among plants, the following trend occurred: dicotyledonous (more sensitive) >> monocotyledonous >> gymnosperm species. Sensitivity was also time and endpoint specific, with endpoints such as lethality and avoidance being less sensitive than reproduction effects. Furthermore, given the breadth of data and toxicity demonstrated by Boric acid, lessons learned from its evaluation are discussed to recommend the properties required by an ideal reference substance for the soil compartment.

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