CatalponolCAS# 34168-56-4 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 34168-56-4 | SDF | Download SDF |
| PubChem ID | 169570 | Appearance | Powder |
| Formula | C15H18O2 | M.Wt | 230.3 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,4S)-4-hydroxy-2-(3-methylbut-2-enyl)-3,4-dihydro-2H-naphthalen-1-one | ||
| SMILES | CC(=CCC1CC(C2=CC=CC=C2C1=O)O)C | ||
| Standard InChIKey | BTQXIESSQVRLCV-RISCZKNCSA-N | ||
| Standard InChI | InChI=1S/C15H18O2/c1-10(2)7-8-11-9-14(16)12-5-3-4-6-13(12)15(11)17/h3-7,11,14,16H,8-9H2,1-2H3/t11-,14+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Ekmanianthe longiflora.
| Description | 1. Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the increased levels of cyclic AMP. |
| Targets | cAMP |
Catalponol Dilution Calculator
Catalponol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.3422 mL | 21.7108 mL | 43.4216 mL | 86.8432 mL | 108.5541 mL |
| 5 mM | 0.8684 mL | 4.3422 mL | 8.6843 mL | 17.3686 mL | 21.7108 mL |
| 10 mM | 0.4342 mL | 2.1711 mL | 4.3422 mL | 8.6843 mL | 10.8554 mL |
| 50 mM | 0.0868 mL | 0.4342 mL | 0.8684 mL | 1.7369 mL | 2.1711 mL |
| 100 mM | 0.0434 mL | 0.2171 mL | 0.4342 mL | 0.8684 mL | 1.0855 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Celastrol
Catalog No.:BCN5986
CAS No.:34157-83-0
- Paludosine
Catalog No.:BCN2010
CAS No.:34137-24-1
- (+)-Sophoranol
Catalog No.:BCN3743
CAS No.:3411-37-8
- Sunitinib malate
Catalog No.:BCC3664
CAS No.:341031-54-7
- Nucleozin
Catalog No.:BCC1811
CAS No.:341001-38-5
- Araloside VII
Catalog No.:BCN8129
CAS No.:340982-22-1
- Fmoc-D-Asp-OtBu
Catalog No.:BCC3470
CAS No.:34098-70-7
- Araloside V
Catalog No.:BCN2466
CAS No.:340963-86-2
- Glycyrrhetic acid 3-O-mono-beta-D-glucuronide
Catalog No.:BCN1453
CAS No.:34096-83-8
- 7-O-Methylbiochanin A
Catalog No.:BCN8212
CAS No.:34086-51-6
- Alpinumisoflavone
Catalog No.:BCN5266
CAS No.:34086-50-5
- (20S)-Protopanaxatriol
Catalog No.:BCN2705
CAS No.:34080-08-5
New Products
- Pterosin Z
Catalog No.:BCN5268
CAS No.:34169-69-2
- Pterosin D
Catalog No.:BCN5269
CAS No.:34169-70-5
- H-Tyr-OMe.HCl
Catalog No.:BCC3127
CAS No.:3417-91-2
- Pterosin B
Catalog No.:BCN7100
CAS No.:34175-96-7
- Propafenone HCl
Catalog No.:BCC5079
CAS No.:34183-22-7
- Actinidic acid
Catalog No.:BCN5270
CAS No.:341971-45-7
- Lys-Bradykinin
Catalog No.:BCC5993
CAS No.:342-10-9
- 3-Methoxyfuran
Catalog No.:BCN5271
CAS No.:3420-57-3
- Dihydroflavokawin B
Catalog No.:BCN5272
CAS No.:3791-76-2
- 7-beta-Hydroxylathyrol
Catalog No.:BCN3413
CAS No.:34208-98-5
- Trachelogenin
Catalog No.:BCN2739
CAS No.:34209-69-3
- Tovopyrifolin C
Catalog No.:BCN6888
CAS No.:34211-53-5
Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells.[Pubmed:20183248]
J Asian Nat Prod Res. 2009 Oct;11(10):867-75.
The effects of Catalponol (1) on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells were investigated. Catalponol at concentration ranges of 1-5 microM increased the intracellular levels of dopamine at 12-48 h. Catalponol at concentrations of up to 10 microM did not alter cell viability. Tyrosine hydroxylase (TH) activity was enhanced by 1 at 3 microM in a time-dependent manner, but aromatic L-amino acid decarboxylase activity was not. Catalponol also increased the intracellular levels of cyclic AMP and TH phosphorylation. In addition, Catalponol at 3 microM associated with L-DOPA (20-50 microM) further enhanced the increases in dopamine levels induced by L-DOPA (50-100 microM) at 24 h. Catalponol at 2-5 microM inhibited L-DOPA (100-200 microM)-induced cytotoxicity at 48 h. These results suggest that 1 enhanced dopamine biosynthesis by inducing TH activity and protected against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the increased levels of cyclic AMP.
Catalponol,34168-56-4,Natural Products, buy Catalponol , Catalponol supplier , purchase Catalponol , Catalponol cost , Catalponol manufacturer , order Catalponol , high purity Catalponol
